In this presentation from Glaucoma Subspecialty Day 2022, Dr. Gustavo De Moraes reviews current evidence on the role of micronutrients, particularly nicotinamide, in glaucoma. He discusses recent studies on the relationship between micronutrients and glaucoma, as well as clinical trials investigating the neuroprotective effects of nicotinamide for glaucoma progression. He also describes lessons learned and what should be considered in future trials examining neuroprotection.