Pyogenic granuloma. A, Clinical appearance, at a site of prior strabismus surgery. B, Histology; this low-magnification photograph shows a pedunculated mass of granulation tissue, with a “spoke-wheel” vascular pattern. C, High magnification shows a mixture of acute and chronic inflammatory cells. Note neutrophils (N), both within the lumen of blood vessels and also infiltrating the tissue. Chronic inflammatory cells are also present, predominantly lymphocytes (L) in this field.